About 4 results found for searched term "Mcl-1 inhibitor 6" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M22513 | Mcl-1 inhibitor 6 | Bcl-2 |
| Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a Kd of 0.23 nM and a Ki of 0.02 μM. Mcl-1 inhibitor 6 possesses superior selectivity over other Bcl-2 family members (Bcl-2, Bcl2A1, Bcl-xL, and Bcl-w, Kd>10 μM). | ||
| M41318 | Mcl-1 inhibitor 16 | Bcl-2 |
| Mcl-1 inhibitor 16 is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. | ||
| M21643 | VU661013 | Bcl-2 |
| VU0661013 | ||
| VU661013 is a novel, potent, selective MCL1 inhibitor with Ki of 97 ± 30 pM to human MCL-1 in a TR-FRET assay. VU661013 destabilizes BIM/MCL1 association, leads to apoptosis in AML, and is active in venetoclax-resistant cells and xenografts. | ||
| M29850 | IMB-XH1 | Bcl-2 |
| IMB-XH1 is an inhibitor of myeloid cell factor 1 (Mcl-1). IMB-XH1 is a non-competitive Delhi metallo-β-lactamase (NDM-1) inhibitor. The IC50s of IMB-XH1 against metallo-β-lactamases NDM-1, IMP-4, ImiS and L1 are 0.4637 μM, 3.980 μM, 0.2287 μM and 1.158 μM, respectively. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
